甘精胰岛素强化治疗2型糖尿病的研究

Study of insulin Glargine on type 2 diabetes

目的 观察甘精胰岛素治疗2型糖尿病患者的降糖效果和安全性。方法 2 7例2型糖尿病伴高血糖(FPG≥1 1mmol/L)患者随机分为A、B 2组进行强化胰岛素治疗,A组为甘精胰岛素治疗组(n =1 3) ;B组为胰岛素泵治疗组(n =1 4 )。2组治疗目标末梢血糖值为空腹≤7.0mmol/L和餐后2h血糖≤1 1 .1mmol/L。结果 2组患者都达到目标血糖值,血糖达标时间无差异,低血糖发生率无差别(P均>0 .0 5 )。结论 甘精胰岛素强化治疗可以良好地控制高血糖,且低血糖发生率低。

Objective It is to observe the lowering sugar effect and safety of insulin Glargine on type 2 diabetes patients. Methods 27 patients with type 2 diabetes and high blood sugar were randomly divided into group A (using insulin Glargine, n=13) and group B (using insulin pump, n=14). The therapeutic targets of the two groups were that fasting blood sugar was ≤7.0 mmol/L and 2 h postprandial blood sugar was ≤11 mmol/L. Results The patients in the two groups achieved blood sugar target. There was no difference in achieveachieve achiethe time of achieving target between the two groups (P>0.05). There was no difference in the incidence of hypoglycemia between the two groups (P>0.05). Conclusions Insulin Glargine intensification therapy can control high blood sugar well and the incidence of hypoglycemia is low.