血清中GST和B－GST的测定对恶性肿瘤的诊断意义

Diagnostic value to determination of serum GST and B-GST for the patients with malignant tumor

本文用ＡｄａｃｈｉＹ法和ＳｈｉｖｅｎｄｒａＶ法分别测定了正常人及肿瘤患者血清中谷胱甘肽硫转移酶（ＧＳＴ）及其同工酶碱性谷胱甘肽硫转移酶（Ｂ－ＧＳＴ）的活性．结果表明：血清中Ｂ－ＧＳＴ活性值在肝癌时较正常明显升高（ｐ＜０．０５），阳性率为５５．６％。血清中ＧＳＴ活性在肝癌、肺癌、乳腺癌、宫颈癌、鼻咽癌及食道癌时与正常人无显著差异（ｐ＞０．０５）。

The activities of glutathione S-transferase (GST) and basic glutatione S-tranferase (B-GST)in serum for healthy adults and patients with tumor were assayed with Adachi method and Shivndra method respectively. In results,serum B-GST activities significantly incresed only in cases ofhepatoma(P<0. 05),the positive rates in 55. 6%,serum GST activities in cases of hepathoma,lung cancer,breast cancer,cancer of uterine cervix,nasophargngeal cancer and cancer of esophaguswere not different significantly as compared to healty adults (P>0. 05).