连钱草中的黄酮类化学成分

Flavonoids from Glechoma Longituba(Nakai) Kupr.

目的:对连钱草全草进行化学成分研究。方法:采用工业酒精提取、硅胶柱层析、ODS柱层析和重结晶等方法。结果:从连钱草全草中分离并鉴定了10个黄酮类化合物,其结构分别为:芹菜素(1)、木犀草素(2)、芹菜素7O葡萄糖醛酸乙酯苷(3)、木犀草素-7-O-葡萄糖醛酸乙酯苷(4)、大波斯菊苷(5)、木犀草素-7-O-葡萄糖苷(6)、山奈酚3O芸香糖苷(7)、芦丁(8)、6-C-阿拉伯糖-8-C-葡萄糖芹菜素(9)和6-C-葡萄糖-8-C-葡萄糖-芹菜素(10)。结论:化合物1～10均为首次从该植物中分离得到。

AIM:To study the chemical constituents of Glechoma longituba.METHODS:Alcoholic extraction,silica gel,ODS column chromatography and recrystallization were used.RESULTS:Ten compounds from Glechoma longituba were isolated and identified as:apigenin,luteolin,apigenin-7-O-β-D-glucuronide ethyl ester,luteolin-7-O-β-D-glucuronide ethyl ester,cosmosiin,luteolin-7-O-β-D-glucoside,kaempferol-3-O-β-D-rutinoside,rutin,6-C-arabinose-8-C-glucose-apigenin,and 6-C-glucose-8-C-glucose-apigenin.CONCLUSION:All of these compounds were isolated from Glechoma longituba for the first time.