男性肺癌血中内分泌激素的测定

Endocrine hormone in the blood of the patients With lung cancer in the male

从１９９１年１０月－１９９３年６月对４５岁以上男性，４４例正常人和８７例肺癌患者血中８种内分泌激素进行测定，肺癌病人治疗前Ｃｏｒｔ、β－ＨＣ、Ｇｌｕｃ和ＰＲＬ明显高于正常人群。８７例肺癌治疗前按不同病理比较，腺癌β－ＨＣＧ明显高于其它病理类型，鳞癌ＰＲＬ高于其它，小细胞未分化Ｇａｓｔ高于其它。４３例肺癌治疗后，ＴＳＨ、ＰＲＬ、Ｃｏｒｔ和Ｇｌｕｅ都明显降低，而ＧＨ则升高，１１例治疗后肿瘤复又增大或远处转移的肺癌患者，再次测定激素水平表明，ＰＲＬ、Ｃｏｒｔ和Ｇｌｕｅ复又升高。这些结果说明部分内分泌激素，可用于男性肺癌的早期诊断或鉴别诊断，有些激素可作为肺癌病理分类的参考。

From 1991.10 to 1993.6,for the males upper 45-years-old,44 normal men and 87 caseswith lung cancer,the 8 kinds of endocrine hormone were monitored. Before treatment, cortison,β-HGG、Glucagon and Prolatin in the patients with adenocacinoma were higher.Prolatin in thesquamous cell cacinoma was higher.After treatment Thyroid stimulating hormone. prolatin.cortison and Glucagon were lowwer,but Growth hormone was higher. The results showed:1.partsof the endocrine hormones were advantageous to early diagnosis and differential diagnosis for thelung cancer.2.some kinds of endocrine hormones were help to the histologic classification of lungcancer.