酶学、B型超声、CT及ERCP检查对慢性胰腺炎与胰腺癌的鉴别诊断价值

CLINICAL SIGNIFICANCE OF ENZYMOLOGIC, ULTRASOUND,COMPUTED TOMOGRAPHY AND ERCP IN DIFFERENUAL DIAGNOSIS OFCHRONIC PANCRETITIS AND PANCREATIC CANCER

对经手术和/或病理证实的130例慢性胰腺炎和101例胰腺癌的酶学、B型超声、CT及ERCP检查对比分析。结果表明胰腺癌组ALP和γ-GT明显高于慢性胰腺炎组（ALP84.9％与32.1％，γ-GT93.8％与57.l％，p＜0.01）。B型超声对慢性胰腺炎与胰腺癌的诊断正确率分别为65.7％与72.9％（p＞0.05），CT分别为64.0％与80.0％（p＞0.05），ERCP分别为37.3％与72.7％（p＜0.01）。结果提示ALP/γ-GT与ERCP对慢性胰腺炎与膜腺癌有鉴别诊断意义。

s: In order to evaluate the clinical significance of enzymologic, ultrasound (US), computed tomography (CT) and ERCP in differential diagnosis(DD) of chronic pancreatitis(CP) and pancreatic cancer (PC). 130 patients with pathologically proven CP and 101 patients with surgically confirmed PC were analysed. The results showed that serum alkaline phosphatase(ALP) and Y-glutamyltranspeptidae(r-GT) levels were higher in PC group in comparison with CP group(ALP,84. 9% vs 32. 1%.r-GT, 93. 8 vs 57. l%.p<0. 01). The accurate diagnosis rate of US was 72. 9% in PC group and 65. 7% in CP group. The accurate diagnosis rate of CT was 80. 0% in PC group and 64. 0% in CP group. No significant difference in DD of US and CT for both CP and PC group (p>0. 05). The accurate diagnosis rate of ERCP in PC was 72. 8% .being higher than that of CP group with on accuratediagnosis rate sb 37. 2%(p<0. 01). The results suggest that ALP/r-GT and ERCP might be helpful for DD of CP and PC in their relative early stage.