低场强MRI不同脉冲序列对脊柱转移瘤敏感性的比较

Comparison of Different Sequences and Protocols in Detecting Spinal Metastases

目的:研究低场强MRI不同脉冲序列在脊柱转移瘤诊断中应用价值,着重研究GR的诊断价值。材料与方法:共51例(病理或临床诊断为脊柱转移瘤),42例为多发病灶,9例为单发病灶(均有恶性肿瘤史)。使用日立MRP-7000AD0.3TMR仪。51例均行SE/T1WI—SAG,FS/T2WI—SAG,其中15例行GR/T2WI—SAG或COR,10例行GD—DTPA增强。结果:评估和比较三个脉冲序列扫描显示的病灶数和特征。低场强MRIGR影像对病变定位和特征显示要优于FS/T2WI;SE/T1WI显示病变数目上与GR无差异,但显示病变特征(病变范围、信号特点等)有局限。结论:GR序列对脊柱转移瘤能提供更多重要的信息,从而对病变作出更准确的定位和定性,是低场强MRI诊断脊柱转移瘤必不可少的扫描序列。

Purpose:To study the application of different pulse sequence at low field strength MRI in the diagnosis of spinal metastases.Materials and Methods:51 Spinal MRI were obtained in 51 patients with metastasis in clinically and pathologically proven cases.42 cases had multiple lesions in the different vertebrae,9 cases with malignancy tumor history had solitary vertebral lesion.All cases were examined with HITACHI MRP-7000AD 0.3 Tesla MRI.MR studies included T_1 and T_2-weighted spin-echo(SE) and T_2*-weighted gradient-refocused (GR) pulse sequences.Results:The number of lesions identified and the characteristics (signal intensity、size,etc.)of each spinal metastatic lesion were assessed and compared by means of the three pulse sequences.Lesion depiction and characterization were superior with T_2*-weighted GR sequences at 0.3T MRI.With the T_1-weighted SE sequence,depiction was similar with GR sequence,but characterization was not so good as GR sequence.Conclusion:The GR sequence provided significant additional information and improved depiction and characterization of spinal metastases at 0.3T MRI.