^(99m)Tc-甲酯异丙基异腈诊断甲状腺肿瘤的初步临床应用

Preliminary Application of ^(99m)Tc-CPI Imaging in Thyroid Tumors

我们对26例有病理证实的甲状腺病变进行了^(99m)Tc-甲酯异丙基异腈(^(99m)Tc-CPI)显像,11例甲状腺恶性肿瘤8例病灶摄取^(99m)Tc-CPI,9例甲状腺癌转移灶8例有^(99m)Tc-CPI浓聚。15例甲状腺良性病变12例^(99m)Tc-CPI显像阴性。与同组患者^(131)I甲状腺扫描相比,^(99m)Tc-CPI显像对甲状腺恶性肿瘤及其转移灶诊断的阳性率高于^(131)I扫描。^(99m)Tc-CPI显像为甲状腺良恶性病变的鉴别及甲状腺癌转移灶的定位诊断提供了一个简便易行的方法。

26 cases of thyroid nodules were studied by 99mTc-DPI imaging and confirmed surgically and pathologically. The positive rate in thyroid cancer was 72. 7%(8/11). 9 thyroid cancer patients presented with metastatic lesions. The positive rate of 99mTc-CPI imaging for lymph node metastasis was 88. 9% (8/9). The positive rate of thyroid cancer diagnosis with 99mTc-CPI scintigra-phy was higher than that of 131I scan,It suggested that 99mTc-CPI imaging seemed to be a simple and useful method for diagnoses of thyroid cancer and its metastasis.