肝细胞性肝癌的磁共振成像定量分析

MRI of Hepatocellular Carcinoma:Quantitative Analysis

对５７例肝细胞性肝癌（ＨＣＣ）的７１处瘤灶用１．０ＴＭＲＩ进行６项定量测定，最小病灶的直径为１．５ｃｍ。分别对６例肝转移癌（ＨＭＣ）、４０例肝海绵状血管瘤（ＨＣＨ）、１１例肝囊肿（ＨＣＹ）的１２、７０、１７处病灶也作了相应的测定。在所测６项数据中，Ｔ２值对ＨＣＣ与ＨＣＨ和ＨＣＹ的鉴别意义最大：ＨＣＣ的Ｔ２值＜９０ｍｓ，ＨＣＨ和ＨＣＹ的Ｔ２值分别＞１００ｍｓ和＞１２０ｍｓ。ＨＣＣ与ＨＭＣ用定量方法较难鉴别。本文还对有关定量测定的一些问题作了简要讨论。

Seventy one lesions in 57 patients with hepatocellular carcinoma(HCC) were measured including T1 value, T2 value,lesion-liver signal intensity ratio and lesion-liver contrast-to-noise ratio on both T1- and T2- weighted images with MRI at 1.0T. The minimal lesion was 1.5 cm in diameter. As comparison,12 hepatic metastases in 6 patients, 70 hepatic cavernous hemangiomas(HCH) in 40patients and 17 hepatic cysts(HCY) in 11 patients were measured in the same way. T2 values could be used to differentiate HCC from HCH and HCY, The T2 value of all HCC was <90ms,andT2 values of all HCH and HCY were>100ms and> 120ms respectively. It was difficult to differentiate HCC from hepatic metastases by quantitative method.