肾放免联检在严重烧伤临床的应用及分析

Clinical Application and Analysis of Renal Radio-immuno Examination in Severe Burns

本文对52例烧伤病人（面积30－90％，Ⅲ度0－66％）各时相的肾功能作了放射免疫七项联检测定。经多方元差分析逐步回归分析的统计学处理结果为：1．血β2-m（β2-微球蛋白）各时相均明显升高。2.尿ALb（尿蛋白）伤后二周明显升高。3．血IgG（免疫球蛋白）伤后前二周明显下降。4．尿IgG（免疫球蛋白）伤后排出增多。5.血THp（粘蛋白）各时相在正常范围内。6.尿THP在伤后两周内升高明显．7．Ⅲ度烧伤面积＞50％BSA，THP升高明显。经验检和统计学处理，得出烧伤面积、血β2-m、血THP升高、血IgG下降与死亡机率显著性相关，对严重烧伤患者的予后判断有一定的临床意义和参考价值。

Renal radio-immuno examinations of 52 cases ofburn (30 to 90% BSA, 0 to 66% third degree burn)were made- Renal function at different time phaseswere analyzed on the basis of the results of theexamination on 7 criteria. The results weresummarized as follows: 1. Blood β2 microglobulincontent increased at different time phases. 2. Urinealbumin content increased at 2 weeks postburn. 3.Blood IgG decreased at 2 weeks postburn. 4. UrineIgG excretion increased postburn. 5. Blood THp levelkept normal at different time phases. 6. Urine THplevel increased at 2 weeks postburn and 7. Patientswith third degree burn area exceeding 50% BSA hadTHp level markedly increased.Statistical analysis showed that increases inblood β2 microglobulin and blood THp and decrease inblood IgG level had significant correlations with themortality. These criteria are of clinical significance inprognosis of severe burn patients.