摘要
观察１２０例糖尿病足坏疽患者加用山莨菪碱治疗前后的甲襞微循环变化。结果表明：治疗前坏疽病人有不同程度的甲襞微循环障碍。山莨菪碱治疗后视野能见度有明显好转，清楚管袢、发夹形管袢、管袢数目增加，袢周和袢顶的出血、渗出减少或者消失；血液流态亦明显改善，团聚流减少（由８５．７％降至２４．３％）。管袢长度、宽度及输入、输出枝直径均有明显改善。甲襞微循环改善的同时，临床坏疽伤口也逐步好转、愈合，足坏疽的治愈率达８３．３％。山莨菪碱能改善糖尿病肢端坏疽病人的甲襞微循环障碍，对坏疽伤口的愈合有益。
Changes of microcirculation in 120 diabetic patients with gangrenous extremities are observed before and after treatment with anisodamine .There are marked microcirculatory disturbances in nailfold of diabeties. After treatment, microcirculation are improved greatly with: 1.the number and clearity of the capillary loops increased, 2. exudates and ecchymoses absorbed in most cases,3. blood cell aggregation lessened and blood velocity increased. 4. the diameters of capillary loops increased. At the same time, the gangrenous wounds healed gradually.It concluded that anisodamine which can improve the microcirculation in diabetics is benifit for the diabetic gangrene treatment.
出处
《微循环学杂志》
1994年第4期16-18,T002,共4页
Chinese Journal of Microcirculation
关键词
山莨菪碱
治疗
糖尿病足坏疽
甲襞微循环
Microcirculation
Diabetes
Gangrenous extremities
Anisodamine
