心瓣膜置换术后的甲襞微循环变化

Changes of Nailfold Microcirculation After Operated Heart Valve Replacement

对３７例心瓣膜置换术后及３０例健康人的甲襞微循环进行了对比观察。结果显示：心瓣膜置换术后患者甲疑微循环在形态、流态、袢周及总积分均高于健康人，具有极显著差异（Ｐ＜０．００１～０．００５）。从而论示风心病心瓣模替换术后，虽促进了心功能的进一步恢复，但其微循环改善较迟和不理想。故认为心瓣膜替换术后，监测微循环变化，对准确把握抗凝治疗，减少术后出血及栓塞等并发症，具有十分重要意义。

Nailfold microcirculation for 37 rheumatic mitral stenosis patients after valve replacement were observed and compared with 30 normal persons.The results showed that the heart valve replacement patients' nailfold microcirculation,form,the total integral was extremely significantly higher than normal controls(P<0.001～0.005).It suggest that after valve replacement,though the recovery of heart function was promoted,the improvement of microcirculation was delayed and not as good as expected.It might be important to monitor the changes of microcirculation for valve replacement patients for better use of anticoagulation drugs after operation in order to decrease complications such as bleeding,embolism,etc.