急性颅脑损伤患者血清SICAM-1和CRP检测的临床意义

Significance of Measurement of Serum SICAM-1 and CRP Levels in Acute Head Injury

目的:探讨了急性颅脑损伤患者血清细胞间粘附分子-1(SICAM-1)和C反应蛋白(CRP)水平及其临床意义。方法:应用ELISA法和免疫法对33例急性颅脑损伤患者进行了血清SICAM-1和CRP水平检测,并与35名正常健康人作比较。结果:急性颅脑损伤患者血清中SICAM-1和CRP水平非常显著地高于正常人组(P<0.01),尤以重型组为甚。结论:测定急性颅脑损伤患者血清中SICAM-1和CRP水平对了解病情,并有助于预后判断。

Objective To explore the clinical significance of changes of serum SICAM-1 and CRP levels in patients suffering from acute head injury. Methods Serum SICAM-1 levels was measured with ELISA and CRP levels with immunological method in 33 patients with acute head injury at admission and 35 controls. Results Serum levels of SICMA-1 and CRP were significantly higher in patients with acute head injury than those in controls (P<0.01), especially in severe cases. Conclusion Detection of serum SICAM-1 and CRP levels in patients with acute head injury can reflect the severity of the injury and contribute to outcome prediction.