消毒硫酸钡用于经皮椎体成形术的实验研究

An experimental study on sterilized barium sulfate (BaSO_4) for vertebroplasty

目的 探索行经皮椎体成形术时所需BaSO4 粉的合适消毒方法。方法 将BaSO4 粉分成干热法消毒组及环氧乙烷消毒组,对其分别进行细菌培养;然后选择2种消毒法制备的BaSO4 粉,将灌注剂按粉液比(g /ml)为3∶2 ,而粉剂中BaSO4 的百分比为2 0 %,分别进行调配。每组制备6个样本,测定其聚合时间、CT值、强度和刚度,对结果进行2组独立样本的t检验。结果 2种消毒法制备的BaSO4粉经细菌培养显示无菌,2组灌注剂间的刚度和强度有明显改变,结果差异有显著性(P <0 .0 5 ) ,干热法消毒组高于环氧乙烷组;2组灌注剂的聚合时间、CT值无显著性差异(P >0 .0 5 )。结论 2种消毒法灭菌效果满意,但干热消毒法组灌注剂材料性能优于环氧乙烷组,是经皮椎体成形术中制备BaSO4 粉的较好消毒方法。

Objective To search the proper sterilizational method of barium for vertebroplasty. Methods Perfusion agents were classified into two groups with ratio of powder/liquid (g/ml) as 3∶2, and the percentage of BaSO 4 in powder was 20%. The barium powder in one group was sterilized by dry-heat and by ethylene oxide in the other. The barium powder of each group was germicultured and the polmerization time, CT value,strength and stiffness were measured respectively including 6 samples.Two independent-samples t text was used for analysis. Results The germiculture in each group was negative. The difference in polmerization time and CT value of each group were not significant(P >0.05), while the strength and stiffness were significantly different (P <0.05). Conclusions Sterilized effects of two groups were satisfied but the dry-heat barium sulfate is superior, more suitable for vertebroplasty.