^(14)C—尿素呼气试验诊断幽门螺杆菌感染

Detection of helicobacter pylori infection by using ^(14)C-urea breath test

目的评估14C-尿素呼气试验诊断幽门螺杆菌感染的诊断价值。方法对220例患者同步完成快速尿素酶试验、病理、14C-尿素呼气试验检查,以病理(HE染色)、快速尿素酶试验均阳性为诊断幽门螺杆菌感染的标准,评价14C-尿素呼气试验对幽门螺杆菌感染的诊断价值。结果14C-尿素呼气试验的敏感性为90%,特异性为98%,准确性为93.4%。结论14C-尿素呼气试验是幽门螺杆菌感染无创伤、敏感和特异的诊断方法。

Objective To evaluate the diagnostic value of 14C-urea breath test (14C-UBT) in detecting helicobacter pylori (HP) infection. Methods The 220 patients were examined with rapid urease test, pathology and 14C-UBT, the positive of pathology and rapid urease test was used as the standard for the diagnosing of HP infection, and the diagnostic value of 14C-UBT in detecting HP infection was evaluated. Results The sensitivity, specificity and accuracy rate of 14C-UBT in the diagnosis of HP infection were 90%, 98% and 93.4%. Conclusion The 14C-UBT is a noninvasive, sensitive and specific diagnostic method in detecting helicobacter pylori infection.