急性实验性高碳酸血症的微循环障碍

An Acute Experiment on Hypercapnia with Microcirculatory Stasis

用吸入法作成小白鼠实验性高碳酸血症,用带彩色电视的微循环显微镜记录和拍照,也应用了微机分析,红细胞电泳,毛细管通透试验,结果:血液高碳酸血症越高,微循环障碍越严重。实验指出,临床上在高碳酸血症时,必须注意纠酸、脱水、红细胞解聚和降低血液粘度。在昏迷时慎用扩张血管药物。

A model of the blood hypercapnia(BHPCO_2) was made by the method of CO_2 inhalation in mice bodies. The exchanges of microcirculatory stasis was observed, photographed, recorded by system of microscope with colour TV; computer analysis, red blood cells electrophorisls and the test of capillaries permeability were used by us. The results showed that higher the BHPCO_2 rises, the more serious the microcirculatory stasis was. The experiment suggests that we must notice to correcter acidosis, dyhydrotion, release the red blood cells aggreation and decrease the blood viscocity for to treat the BHPCO_2 in clinic. If you wanted to use the drugs of vasodilatation in coma, you must adopt a prudent policy.