摘要
采用硫代巴比妥酸反应产物比色法检测了２７例小儿癫痫（继发性癫痫１６例，原发性癫痫１１例），２０例健康小儿血液红细胞过氧化脂质含量，其结果分别为６６９．１９±１２１．９２、５５３．２１±１３３．８６和４８３．８４±８５．４５ｎｍｏｌ／ｇ·Ｈｂ。继发性癫痫组红细胞过氧化脂质明显高于原发性癫痫组和健康对照组（Ｐ＜０．０５，Ｐ＜０．０１）．原发性癫痫组和健康对照组比较无显著差异性（Ｐ＞０．０５）．提示继发性癫痫患儿体内的病理性脂质过氧化反应明显增强。
Using the colorimetry of the reaction of thiobarbituric acid(TBA), RBC-LPO concentrations were measured. The RBC-LPO values(669. 19 ± l21. 92 nmol/g. Hb) in the symptomatic epilepsy group were higher than that in the idiopathic epilepsy group (553. 21±133. 86 nmol/g· Hb) and controls(483. 84±85. 45 nmol/g· Hb), (P<0.05,P<0. 01).The BRC-LPO values have no significant difference between the idopathic epilepsy group and controls. The result showed that the reaction of pathologic lipid peroxidation in symptomatic epileptic children is significantly high.
