高血压微循环与体循环动力学临床研究系列(下)——Ⅶ.高血压病人毛细血管压与某些血流动力学指标之间关系的探讨

Interaction of Capillary Pressure and Some Hemodynamics in Patients with Essential Hypertension

用间接法测定30例高血压病人甲襞毛细血管压明显高于正常血压组(68.68±19.42mmHg对43.11±10.30mmHg,1mmHg=1/7.5kPa,P<0.01)高血压组用心痛定或巯甲丙脯酸干预后,毛细血管压明显下降(57.4l±14.78对68.68±19.42mmHg,P<0.02)。高血压病人毛细血管与肱动脉舒张压呈正相关(r=0.731,P<0.05),降压治疗后,毛细血管压与甲襞毛细血管密度呈负相关(r=0.697,P<0.05),提示高血压病人检查毛细血管压可作为无创性评价外周阻力的临床指标之一。

The nailfold capillary blood pressure was estimated by inderect method in both 30 hypertensive patients and 30 normotensive subjects. The results showed that the capillary pressure in hypertension group was elevated significantly (68.68±19.42 vs. 43.11±10.30, P<0.01), and positive relation between both of capillary pressure and the diastolic blood pressure(r=0.731, P<0.05). After the hypertensive patients treated with Nefidipine, the capillary pressure correlated inversly with capillary density (r=-0.697, P<0.05). It suggested that the studied on nailfold capillary pressure would be helped understanding a interaction of macro-microcirculatory hemodynamics and also may be regarded as a index of estimating periphery resistance in the patients with hypertension.