摘要
使用α-受体激动剂可乐宁对60例海洛因成瘾者戒毒治疗,并与亚冬眠疗法对照进行观察。戒毒期间,可乐宁使用有效率为96.6%,与对照组(71.6%)比较,具有非常显著性差异,证明可乐宁的治疗效果可靠。根据海洛因戒断症状的临床表现和体征,本文将可乐宁治疗分为两组,对药物效能进行观察,治疗后72 h两组疗效结果提示,治疗早期配合使用抗焦虑类药物可以明显提高治疗药物的抑制效能,并能缓解与之伴随的主观不适诸症。结果说明可乐宁适用于各种类型的海洛因成瘾者的戒毒治疗。
We conducted a study to assess the clinical usefulness of clonidine in the treatment of heroin detoxification. 60 cases of heroin addicts were detoxified with α-receptor agonist clonidine compared with sub-sleep therapy. The effective rate of clonidine was 96. 6% , which was signifi- cantly higher than that of sub-sleep therapy (71.6%). Half of the patients receiving clonidine therapy were concomitantly treated with anti- axiety drugs at first 3 days and they showed fewer objective abstinence signs and subjective abstinence symptoms. The efficacy of clonidine in heroin detoxification is confirmed in this study.
关键词
可乐宁
治疗
海洛因成瘾
疗效观察
drug dependence
heroin
clonidine
detoxification
withdrawal symptom
