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脂肪酸对机体免疫细胞的影响 被引量：1

Effects of fatty acids on immune cell function
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摘要 脂肪酸通过改变免疫细胞膜的组成，细胞内信使传递和细胞因子来调节免疫细胞的功能。n－6系多不饱和脂肪酸具有免疫抑制作用，n－3系多不饱和脂肪酸可以部分抵销这种免疫抑制作用。 Fatty acids may medulate immune cell function by their effects upon the cell membrane composition, cytokines and intracellular regulatory mechanisms. N-6 polyunsaturated fatty acids (PUFA)had an immunosuppressive effect, while n-3 PUFA could partly weaken the immunosuppression of n-6 PUFA.
作者 蔡文伟 花天放
机构地区 上海市第一人民医院普外科
出处 《中国临床营养杂志》 1998年第3期131-134,共4页 Chinese Journal of Clinical Nutrition
关键词 机体免疫细胞 n-3系多不饱和脂肪酸 免疫抑制作用 细胞内信使 细胞因子 细胞膜 Polyunsaturated fatty acid Immunosuppression
分类号 R512.620.5 [医药卫生—内科学] R543.01 [医药卫生—心血管疾病]
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  • 2Wang Y. W.,et al. Dietary polyunsaturated fatty acids alter lymphocyte subset proportion and proliferation,serum immunoglobulin G concentration,and immune tissue development in chicks[J]. Poult Sci.,2000,79 (12): 1741-1748.
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  • 6Robinson L. E.,et al. R3230AC rat mammary tumor and dietary long-chain (n-3) fatty acids change immune cell composition and function during mitogen activation[J]. J. Nutr Sci.,2001,(2):2021-2027.
  • 7Sanderson P.,et al. Effects of dietary lipid manipulation upon graft vs host and host vs graft responses in the rat [J]. CellImmunol.,1995,164(2) :240-247.
  • 8Serizawa H.,et al. Reversal of altered intestinal mucosal immunity in rats fed elemental diet by supplementation of oleic acid [J]. J Gastroenterol Hepatol.,1996,11(9):811-818.
  • 9Catherine J. Field,et al. Nutrients and their role in host resistance to infection [J]. J. Leukocyte Biology, 2002,71 (1):16-32.
  • 10Fritsche K. L.,et al. Effect of dietary fat source on antibody production and lymphocyte proliferation in chickens [J].Poultry Sci.,1991,(70) :611-617.

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中国临床营养杂志
1998年 第3期

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