摘要
本实验在40只大鼠经伺服零测压技术测定的肾脏微血管内压力分布及其ANP的作用均随血管树各段的口径变化而改变。分析小球前各段血管的压力降所占动脉总压降的比例得知:小叶间动脉占总压降的88％。肾小球毛细血管和出球小动脉亦具有较大的压力降。正常对照情况下,肾小球前血管内的压力分布与内径呈直线相关(r=0.869,n=65,P<0.01),其回归方程为平均压()=34.71±0.798×血管内径(D)。给ANP后肾小球前血管内的压力与内径仍呈直线相关(r=0.931,P<0.01),回归方程式为()=38.53+0.765D,其曲线右上移。本文结果提示,肾小球前微血管内压力分布与血管内径密切相关。小叶间动脉的阻力较大。
The intravascular hydrostatic pressures in mierovessels of hydronephrotic kidney of rats were measured and effect of atrial natriuretic peptide(ANP) was observed. The results showed that 88% of the total pressure drop across vasculature from arcuate artery fo glomeruli occurs in the interlobular artery and diameter of preglomerular microvessels. ANP caused an increase in diameter and pressure in the microvessels, but did not alter the pressure profile in the renal microvessels. It is suggested that the interlobular arteries are potentially important in controlling glomerular perfusion.
出处
《微循环学杂志》
1991年第1期12-15,共4页
Chinese Journal of Microcirculation
