犬急性心肌缺血再灌注损伤 2、微细结构变化的法医病理学研究

Reperfusion Injury to Acute Post-ischemic Myocardium in Dogs-A forensic pathological study of microscopical changes

心脏性猝死占猝死的首位，而缺血性心脏病又占心脏性猝死的首位。然而猝死的尸检表明只有5％～40％发现有心肌梗塞的证据，而绝大部分心脏性猝死未见典型的病理变化。事实上很多心脏性猝死除由器质性病变所致外尚有很多情况是由于冠脉机能突变而且还有痉挛、纤凝、纤溶和再灌注损伤问题。临床缺血性心脏病患者中确有相当一部分患者是由于冠状动脉痉挛而引起的，

The experimental study showed the results that the early reperfusion of postischemic myocardium may cause the necrotic change of myocardium to enlarge and to formed multiple micscopical necrotic focuses. So the study demonstreted the presence of reperfusion injury of post-ischemic myocardium.