期刊文献+

脊髓蛛网膜下腔和脑室注射GABA对大鼠丘脑束旁核痛反应神经元电活动的影响 被引量:2

THE INFLUENCE OF GABA INJECTED INTO CEREBRAL VENTRICLE ON ELECTRICAL ACTIVITIES OF PAIN-EXCITATION NEURONS AND PAIN-INHIBITION NEURONS IN NUCLEUS PARAFASCICULARIS OF THE THALAMUS OF RATS
下载PDF
导出
摘要 实验用Wistar大鼠42只,观察脊髓蛛网膜下腔注射GABA250μg/10μl或脑室注射GABA200μg/20μl对丘脑束旁核痛兴奋神经元(PEN)和痛抑制神经元(PIN)电活动的影响,探讨中枢不同部位外源性GABA对痛觉的调制作用。 The influence of intraventricular injection of GABA on electrical activities of PEN and PIN in nucleus parafascicularis of the thalamus of rats was studied.The results showed that GABA could significantly inhibit the electrical discharges of PEN and increase the electrical discharges of PIN.So it was believed that intraventricularly injected GABA could antagonize or partly antagonize the excitatory action of noxious stimuli and might thus produce analgesia.
出处 《针刺研究》 CAS CSCD 1989年第1期83-84,共2页 Acupuncture Research
基金 中国科学院基金会资助(生85-278)
  • 相关文献

参考文献5

  • 1李玉荣,张季叶,孙明智.大鼠视前区和束旁核中痛兴奋和痛抑制神经元同时电活动的研究[J]针刺研究,1984(02).
  • 2屈智超,范少光,韩济生.大鼠脑内γ-氨基丁酸对电针镇痛和吗啡镇痛的对抗作用[J]生理学报,1983(04).
  • 3孙明智,陈兰生,王滨明,孙二堂,张季叶.丘脑束旁核痛兴奋神经元和痛抑制神经元电活动的研究[J]动物学报,1982(01).
  • 4谢贻芳,乔健天.刺激兔中脑导水管周围灰质对束旁核单位放电的影响[J]生理学报,1981(02).
  • 5韩济生.中枢神经介质概论[M]科学出版社,1980.

同被引文献13

  • 1韩济生.针刺镇痛及其有关的神经通路和神经介质[J].生理科学进展,1984,15(4):294-294.
  • 2Yoneda Y,Takashima S,Kuriyama K.Possible in volvement of GABA in morphine analgesia [J].Biochem Pharmacol,1976,25(23):2669-2670.
  • 3Lapeyre S,Mauborgne A,Becker C,et al.Subcutaneous formalin enhances outflow of met-enkephalin- and cholecystokinin-like materiais in the rat nucleus accumbens [J].Naunyn Schmiedebergs Arch Pharmacol,2001,363(4) :399-406.
  • 4Pellegrino LJ,Pellegrino AS,Cushman AJ.A stereotaxic atlas of the rats brain[M].New York: Plenum Press,1979.33-38.
  • 5Meredith GE.The synptic framework for chemical singaling in nucleus accumbens[J].Acad Sci,1999,877: 140-156.
  • 6Lapeyre S, Mauborgne A, Becker C, et al. Subcutaneous formalin enhances outflow of met-enkephalin-and cholecystokinin-like materials in the rat nucleus accumbens.Naunyn Schmiedebergs Arch Pharmacol 2001;363(4):399-406
  • 7Malun D. Synaptic relationships between GABA-immunoreactive neurons and an identified uniglomerular projection neuron in the antennal lobe of Periplaneta americana: a double-labeling electron microscopic study. Histochemistry 1991;96(3):197-207
  • 8庞志平,徐天乐,李继硕.GABA_A受体的细胞内调控及其机制[J].中国药理学通报,1998,14(S1):60-62. 被引量:8
  • 9朱丽霞,莫孝荣,叶燕燕,吉长福.脑内GABA参与针刺镇痛吗?[J].针刺研究,2001,26(3):199-200. 被引量:6
  • 10赵妍君,刘应兵,阴正勤.伏膈核棘状神经元的电生理学特性[J].国外医学(生理病理科学与临床分册),2002,22(3):233-235. 被引量:4

引证文献2

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部