电圈切除术对宫颈病变诊断治疗价值的临床分析

Clinical analysis of Loop Electrosurgical Excision Procedure in Diagnosis and Treatment of Cervical Lesions

目的评估宫颈电圈环切术(LEEP)对宫颈病变的诊断治疗价值。方法对169例宫颈病变患者行电子阴道镜下宫颈多点活检及LEEP术,将LEEP术前电子阴道镜下多点活检的诊断结果与LEEP术后病理诊断结果进行对照分析。结果与LEEP术前电子阴道镜下宫颈多点活检的诊断结果相比,169例LEEP术后病理诊断级别升高者有41例。电子阴道镜下宫颈多点活检诊断宫颈病变与最终诊断的符合率为75.7%(128/169)。电子阴道镜下多点活检与LEEP术后标本病理诊断有显著性差异(P<0.05)。结论LEEP术具有疗效好、操作简单、安全,术后并发症少、且可提供完整的病理标本等优点。对宫颈病变特别是慢性宫颈炎及宫颈上皮内瘤变(CIN)是1种非常理想的诊断、治疗手段。

Objective To evaluate loop electrosurgical excision procedure(LEEP) in the diagnosis and treatment of cervical diseases.Methods A total of 169 patients with cervical lesions received colposcopy-guided biopsy following by LEEP.The pathological diagnosis was compared before and after LEEP.Results The pathological grade of ultimate diagnosis after LEEP was increased,compare with biopsy-based diagnosis before LEEP in 41 cases.The correction rate of the diagnosis by colposcopy-guided biopsy was 75.7%(128/169).There was significant difference in diagnosis between colposcopy-guided biopsy and specimens after LEEP(P< 0.05).Conclusion LEEP is safe and easily performed with good therapeutic effect and less morbidity.The whole specimen can be provided by LEEP for pathological examination.LEEP is an ideal method for diagnosis and treatment of cervical lesions,especially for chronic cervicitis and cervical intraepithelial neoplasia.