血液透析患者体感诱发电位的研究

The Study of the Somatosensory Evoked Potential(SEP) of the Blood Dialysis Patients

目的:观察血液透析患者体感诱发电位(SEP)的改变,探讨其机理及诊断价值。方法:对29例血液透析患者分组进行SEP检测,与正常人对照,同时行相关因素分析。结果:血液透析患者SEP各波潜伏期异常发生率为83%,与正常对照组比较各波均有明显差异(P<0.01),透析后各波潜伏期均有不同程度改善,与透析前比较有显著性差异(P<0.05),透析超过6个月后,各波潜伏期与透析前比较无显著性差异。相关分析显示SEP潜伏期与血尿素氮(BUN)呈正相关性。结论:SEP可以作为评定血液透析患者神经系统病变改善的疗效指标之一。

Objective: To observe the changes of the (SEP) of the blood dialysis patients, investigate its mechanism and diagnostic value. Method: The SEP of the blood dialysis patients were detected, and the correlation factors were analyzed. Result: The rate of abnormal eclipse period were 83% in all electronic waves of SEP of the blood dialysis patients, compared with normal group all the waves had significant differences(p<0.01). After dialysis the eclipse period of all the waves had some degrees of improvement, and had significant differences compared with that of predialysis period(p<0.05).When dialysis period exceed 6 months, the waves eclipse period had no difference with predialysis period. It was showed that the eclipse period had positive correlation with the BUN parameter. Conclusion: The SEP can be considered as one of the evaluation indexes of the neurological system affection for blood dialysis patients.