202例住院药疹患者致病药物临床分析

Clinical Analysis of 202 Inpatients with Drug Eruption

目的:观察药疹与致病药物之间的关系。方法:通过对202例住院药疹的致病药物进行临床分析。结果:引起或可能引起药疹的药物有20余类,排在前5位的分别是:抗感染药、解热镇痛药、抗痛风药、抗癫痫药、生物制品等。多型性红斑药疹是最常见的,其次为荨麻疹型。生物制品和呋喃唑酮多引起荨麻疹型药疹;磺胺类药多引起固定型药疹。结论:不同致病药物与不同药疹类型之间存在某些内在联系。

Objective: To observe the relationship between drug eruptions and related drugs. Method: Analysing the clinical data of 202 inpatients with drug eruption. Result: It was found that there were more than 20 kinds of drug involved.The allergic drugs include antibiotics,antifebile and antalgic,antiepilepsy agents,antigoutagents,biological preparations which occupy the first 5 places.The type of erythema multiforme was the most commom type in the drug eruptions,then uricaria type.Biological preparations and Furazolidone can produce urticaria type,while the SMZ can produce fixed drug eruption.Conclusion: There are inside relationship between drug eruptions and related drugs.Special drugs can produce special drug eruptions.