膀胱移行细胞癌术后复发影响因素的COX回归分析

The recurrence risk factors in postoperative patients with transitional cell carcinoma of bladder

目的:探讨膀胱移行细胞癌术后复发的影响因素。方法:对139例膀胱移行细胞癌患者的性别、年龄、族别、病理分级、临床分期、肿瘤直径大小、肿瘤数目、手术方式8项因素与复发时间进行COX回归分析。结果:单因素分析表明年龄、手术方式、肿瘤数目3项因素对于肿瘤复发的相对危险差异有统计学意义(P<0.05),纳入COX回归模型后其中手术方式、肿瘤数目与复发明显相关(P<0.05)。结论:多发肿瘤的复发时间短于单发肿瘤,而恰当的手术方式则可明显延长复发时间。

Objective: To study the recurrence related factors in postoperative patients with transitional cell carcinoma of bladder. Methods: An analysis on recurrence in 139 cases postoperative patients with transitional cell carcinoma from 1995 to 2002. Results: The most important was the operation methods,the hazards ratio is 0.680 9 (P<0.05), followed by tumor number (Hr=1.643 8, P<0.05). Conclusions: Tumor number is the hazards factor to the recurrence, or the operational method is the protective factor against recurrence.