1,6-二磷酸果糖钙盐的制备研究

Synthesis of calcium fructose-1,6-diphosphate

目的研究1,6二磷酸果糖(FDP)钙盐3种制备方法对收率和钙盐中FDP含量的影响。方法采用直接沉淀法、乙醇沉淀法、离子交换树脂法3种方法制备FDP钙盐并测定钙盐中的FDP含量。结果直接沉淀法收率86%、钙盐的FDP含量为22.3%;乙醇沉淀法收率92%、钙盐的FDP含量为43.8%;离子交换树脂法收率42%、钙盐的FDP含量为48.7%。结论3种钙盐制备方法各有优点,生产时可根据需要选用合适的方法。

Three methods, namely direct precipitation, ethanol precipitation and ion-exchange resin, were used for the purification of calcium fructous-1,6-diphosphate.The yield of the calcium salt and content of 1,6-diphosphate were 86% and 22.3% after direct precipitation, 92% and 43.8% after ethanol precipitation, 42% and 48.7% after ion-exchange isolation on anion-exchange resin, respectively.