广州地区健康成年人血液流变学指标参考值的调查分析

The Investigation of the Hemorheological Reference Value in Healthy People of Guangzhou

目的 探讨广州地区健康成年人血液流变学指标参考值范围并进行分析。方法 测定5 0 3名健康成年人血液流变学指标,并按性别和年龄组进行统计分析。结果 男性和女性全血粘度低切、中切、高切参考值范围分别为10 .5 5±1.4 1、6 .2 8±0 .6 5和5 2 0±0 .5 3,8.96±1.32、5 .4 7±0 .5 7和4 .5 0±0 .5 0 ;血浆粘度分别为1.36±0 .12和1.38±0 .11;红细胞压积(HCT)分别为4 4 .38±3.0 2和39.6 0±2 .99。男女除血浆粘度值外,其他各项血液流变学指标均有显著性差异(P <0 .0 1) ,同性别不同年龄组间无显著差异(P >0 0 5 )。与北京地区血液流变学各参考值比较,男性除全血高切粘度外其它四项均有显著性差异(P<0 .0 1) ,女性五项指标除HCT外均有显著性差异(P <0 .0 1)。结论 各参数值与文献报道各有差异,所以有必要确立本地区健康成年人参考值范围,为临床提供准确依据。

Objective To investigate hemorheological reference value in healthy people of Guangzhou.Method The hemorheological indices were measured and statistics analysis was done according to different age and sex in 503 healthy people.Results Low shear rate,middle shear rate and high shear rate viscosities of the whole blood in the male group and female group were,respectively,10.55±1.41?6.28±0.65 and 5.20±0.53,8.96±1.32?5.47±0.57 and 4.50±0.50;Plasma viscosity,respectively,were 1.36±0.12 and 1.38±0.11;HCT,respectively were 44.38±3.02 and 39.60±2.99.Between the groups of sex,the discrepancy of the viscosity is significant(P<0.01)except for the indices of plasma viscosity and in the same sex the discrepancy of the viscosity is not significant(P>0.05) between the groups of age.Compared with Beijing,the discrepancy of hemorheological indices in male is significant(P<0.01)except for the indices of high shear rate viscosities,and the discrepancy of the hemorheological indices in female is also significant(P<0.01)except for the indices of HCT.Conclusion In different geographical regions,it is necessary to establish the exact reference value for clinic diagnosis.