孕期维生素A营养与婴儿体格生长相关性研究

Correlation between Vitmin A levels of pregnant women and growth of infants

目的:了解孕妇和新生儿维生素A(VA)营养状况及对婴幼儿体格生长发育的影响。方法:随机调查重庆铜梁县三所医院健康待产妇女及其新生儿维生素A水平,随访上述儿童体格发育情况。结果:共调查143例孕妇血清VA水平为(1.05±0.350)μmol/L,新生儿脐血VA水平为(0.71±0.155)μmol/L,孕妇亚临床维生素A缺乏(SVAD)检出率为17.0%,可疑SVAD为33.3%。新生儿SVAD检出率为45.5%,可疑SVAD53.1%。母亲血VA水平主要受母亲饮食习惯的影响(标准偏回归系数为0.191,P<0.05)。新生儿VA水平主要受母亲血清VA水平影响。母亲血清VA水平与脐带血VA水平呈正相关(r=0.212,P<0.05)。结论:重庆市远郊县孕妇存在中度VAD问题,胎儿期VA营养状况与婴儿体格生长未见明显相关关系。

Objective: To explore the effect of vitA levels of pregnant women and neonates on the development of infants. Methods: We enrolled eligible healthy pregnant women and their neonates from the 3 hospitals in Tongliang, Chongqing. Their VitA levels were measured and the infants’physical development was followed-up at 1 year age. Results: VitA levels were (1.05 ± 0.350) μmol/L and (0.71± 0.155) μmol/L in the 143 pregnant women chosen and their neonates. The determinable rates of VAD were 17.0% and 45.5% respectively in the pregnant women and their neonates; SVAD rates were 33.3% and 53.1% respectively. VitA level of mothers was mainly influenced by food habit(β = 0.191, P < 0.05). VitA level of neonates was mainly influenced by mother’s VitA concentration. There was a positive geographical correlation between mother's VitA level and neonate's VitA level( r = 0.212, P < 0.05). Conclusion: The pregnant women in the counties of Chongqing have problems of VDA on the medium level. Correlation between VitA levels of pregnant women and neonates and growth of infants and toddlers is not significant.