健脾消胀颗粒治疗功能性消化不良脾虚气滞证60例临床观察

Clinical Observation on 60 Cases of Functional Dyspepsia with Stagnation of Qi due to Spleen Deficiency Treated by Jianpi Xiaozhang Granule

目的:观察健脾消胀颗粒对功能性消化不良痞满脾虚气滞证患者的治疗效果和安全性。方法:120例患者随机分为两组,治疗组60例服健脾消胀颗粒;对照组60例服吗丁啉。观察症状、舌象、脉象、钡条胃排空情况。结果:治疗组症状较治疗前明显好转,治疗后胃排空也比治疗前明显好转,两组比较无明显差异(P>0.05)。两组均未发现不良反应。结论:健脾消胀颗粒治疗功能性消化不良脾虚气滞证临床疗效明显,且与吗丁啉作用相近。

Objective:To observe therapeutic effect and safety of Jianpi Xiaozhang Granule for treatment of functional dyspepsia with stagnation of Qi due to spleen deficiency.Methods:120 cases were randomly divided into two groups,a treatment group(n=60) treated by Jianpi Xiaozhang Granule and a control group(n=60)treated by motilium.Their symptoms,picture of the tongue,pulse condition and gastric emptying of barium were observed.Results:After treatment,symptoms and gastric emptying in the treatment group improved significantly,with no significant difference as compared with the control group(P>0.05),and no adverse reaction was found in both groups.Conclusion:Jianpi Xiaozhang Granule and motilium have obvious and similar therapeutic effect on functional dyspepsia with stagnation of Qi due to spleen deficiency.