2Bergstrom JD, Bostedor RG, Masarachia, PJ, et al. Alendronate is a specific,nanomolar inhibitor of farnesyl diphosphate synthase[J].Arch Biochem Biophys,2000,373:231-241.
3Mackie PS, Fisher JL, Zhou H, et al. Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line[J]. J Cancer(Br),2001,6:951-958.
4Lee MV, Fong EM, Singer FR,et al. Bisphosphonate treatment inhibits the growth of prostate cancer cells[J]. Cancer Res,2001,15:2602-2608.
5Peyruchaud O, Winding B, Pecheur I, et al. Early detection of bone metastases in a murine model using fluorescent human breast cancer cells:application to the use of the bisphosphonate zoledronic acid in the treatment of osteolytic lesions[J]. J Bone Miner Res, 2001,16:2027 - 2034.
6Mackie PS, Fisher JL, Zhou H, Choong PF. Bisphosphonates regulate cell growth and gene expression in the UMR 106-01 clonal rat osteosarcoma cell line[J]. J Cancer(Br) 2001,84:951 - 958.
7Senaratne SG, Pirianov G, Mansi JL,et al. Bisphosphonates induce apoptosis in human breast cancer cell lines[J]. J Cancer(Br), 2000,82:1459-1468.
8Boissier S, Ferreras M, Peyruchaud O, et al. Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases[J]. Cancer Res ,2000,60:2949-2954.
9Jadgev SP, Coleman RE, Shipman CM ,et al. The bisphosphonate,zoledronic acid,induces apoptosis of breast cancer cells:evidence for synergy with paclitaxel[J]. J Cancer(Br),2001,84:1126-1134.
10Senaratne SG, Mansi JL, Colston KW. The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome release inbreast cancer cells[J]. J Cancer(Br),2002,86: 1479 - 1486.
二级参考文献5
1[1]Heersche JM,Lees R,Manolson F,et al.Osteoclast size correlates with differences in resorptive activity[J].Bone,2001,28:s 163.
2[2]Espinosa L,Paret L,Ojeda C,et al.Osteoclast spreading is correlated with spontaneous activation of a calcium-dapendent potassium current[J].Bone,2001,28:s 168.
3[3]Ito M,Amizuka N,Nakajima,et al.Ultrastructural and cytochemical studyies on cell death of osteoclast induced by bisphosphonate treatment[J].Bone,1999,25:447-452.
4[4]Russell Rgg,Roger MJ.Bisphosphonates:from the laboratory to the clinic and back again[J].Bone,1999,25:97-106.
5[5]Murrills RJ.In vitro bone resorption assays.In Rooden CA Eds.Principles of Bone Biology[M].Academic Press,Inc.1996,1239-1251.
