精神分裂症患者家庭干预前后家庭支持与生活质量相关性研究

Correlation Between Support and Life Quality in Patients with Schizophrenia

目的探讨家庭干预对精神分裂症患者家庭支持和生活质量改善的可行性和有效性。方法将146例精神分裂症患者随机分为观察组(74例)和对照组(72例),对照组给予常规抗精神病药物治疗,行常规健康教育;观察组在此基础上给予家庭干预1年,干预前后分别采用家庭关怀指数问卷(APGAR)和生活质量评定量表(LQOL)对患者进行评定。结果观察组干预后APGAR、LQOL总分及各因子分(除居住环境、法律安全因子外)显著高于对照组(均P<0.05);观察组患者的家庭支持与工作状况、闲暇活动、家庭关系、社会交往、健康、总体生活状况呈正相关(P<0.05,P<0.01)。结论家庭干预有利于指导家属向患者提供有效的家庭支持,提高患者生活质量。

Objective To explore the feasibility and the effect of improving family support and life quality through family intervention in patients with schizophrenia.Methods One hundred and forty-three patients with schizophrenia were randomly divided into two groups: 72 patients in control group were routinely treated with antipsychotics and 74 patients in trial group were subjected to family intervention besides antipsychotics for one year. All patients were assessed by Family APGAR Index and Lancashire Quality of Life Profile (LQOL) before and after intervention.Results After intervention, the total score and all factor score in trial group were obviously higher than in control group, except for factor scores of reside environment and law security (all P<0.05). There was a positive correlation between family support and condition of job, leisure activity, family relationship, social communication, health and total life condition (P<0.05, P<0.01).Conclusion Family intervention is useful for teaching relatives of patients to offer effective family support to improve patient's life quality.