摘要
介绍普瑞巴林的物理性质及其6种分别以4-甲基戊酸和异戊醛为原料的不同合成方法。讨论了普瑞巴林的药理作用、药动学和不良反应,并对其市场前景作了展望。
The physical property of pregabalin and six different synthetic routes for preparing pregabalin starting with 4-methyl valeric acid and isovaleraldehyde were introduced separately. And pharmacology, pharmacokinetics and harmful effects of pregabalin were discussed in brief. Finally, the market prospect was forecasted.
出处
《精细与专用化学品》
CAS
2005年第10期14-17,共4页
Fine and Specialty Chemicals