鱼腥草注射液雾化吸入治疗小儿疱疹性咽峡炎疗效观察

The effect of aerosolized herba hauttuyniae inhalation on pediatric herpangina

目的探讨鱼腥草注射液雾化吸入治疗小儿疱疹性咽峡炎的疗效,以找出一种治疗该病的简单方便、痛苦小的方法。方法将263例疱疹性咽峡炎患儿随机分为2组,治疗组132例予以鱼腥草注射液雾化吸入,对照组131例予利巴韦林10mg(kg·d)静脉滴注,连续3～5d。2组对症治疗相同,考虑合并细菌感染者加口服抗生素。观察患儿退热时间、疱疹消退时间,并比较疗效。结果治疗组在退热时间、疱疹消退时间均较对照组缩短,差异有显著性意义(P<0.01)。治疗组总有效率为94.7%,对照组总有效率为85.5%,2组比较差异有显著性意义(P<0.05)。结论鱼腥草注射液雾化吸入治疗小儿疱疹性咽峡炎有助于缩短病程、提高疗效,减少痛苦。

Objective To investigate the therapeutic effect of aerosolized herba hauttuyniae inhalation on pediatric herpangina.Methods 263 pediatric cases with herpangina were randomized to the treatment group and the control group.Patients in the treatment group inhaled aerosolized herba hauttuyniae injection.While intravenous drip Ribavirin 0f 10 mg/(kg·d) for 3～5 days was administered in the control group.Antibiotics were given by oral if bacteria infection occurred in both groups.The other treatment in the two groups were similar.The length of fever and herpes existing were observed. Results The length of fever and herpes existing decreased significantly in comparison with that of the control group (P<~0.01 ).The total effective rate was 94.7% in the treatment group and 85.5% in the control group, there was significant difference in total effective rate between the two groups (P<0.05).Conclusion Aerosolized herba hauttuyniae inhalation could produce a better treatment effect and shorten the period of pediatric herpangina.