脓腔内注射药物治疗结核性脓胸疗效观察

Observation on the effect of results of intrathoracic injection for treatment of tuberculous empyema.

目的观察胸腔注射异烟肼、左氧氟沙星、尿激酶治疗结核性脓胸的效果。方法收治结核性脓胸病人80例,随机分为两组。对照组常规化疗基础上加以脓腔冲洗,碱化脓腔环境,异烟肼脓腔注入治疗;治疗组脓腔注射异烟肼、左氧氟沙星及尿激酶,其它治疗方法同对照组。结果对照组治疗总有效率为75%,治疗组总有效率为95%,二组差异有显著性(P<0.01)。结论脓腔注射异烟肼、左氧氟沙星、尿激酶能减少脓腔分隔和多房形成,增强抗结核分枝杆菌的作用。

Objective To observe the curative effect of Rimifon, Levofloxacin and urakinase injected intrapleurally on tuberculous pyothorax patients. Methods Eighty patients with tubculous pyothorax were devided into two groups; treatment group and control group.The patients in control group were injected with Rimifon intrapleurally based on pleural lavage, alkalization and general treatment, and the patients in the treatment group were injected with Rimifon. Levofioxacin and urakinase intrapleurally, The other therapies were the same in both groups. Results The effective rate in the treatment group was 95%,while it was 75% in the control group,the rate in the treatment group was significantly higher than the control group(P<0.01). Conclusion Rimif6n. Levofioxacin and urakinase injected intrapleurally can not only reduce pleura adhesion ,loculation and thicking of the pleura but also show the effect against Mycobaclerium tuberculosis.