母乳喂养与代乳品喂养新生儿血中胃泌素及胃动素水平比较

Comparative Study of Serum Gastrin and Plasma Motilin Levels Between Breast-fed and Formual-fed Newborn Infants

目的比较正常新生儿母乳喂养与代乳品喂养情况下血中胃泌素及胃动素水平的差异方法应用放射免疫分析技术对100例正常足月新生儿(其中比较组50例由母乳喂养,对照组50例由代乳品喂养)的血清胃泌素、血浆胃动素进行了检测和统计分析。结果比较组胃泌素和胃动素水平明显高于对照组,表明母乳中胃泌素、胃动素进入新生儿体内后与内源性胃泌素、胃动素具有类似的生物活性,能补充新生儿体内的不足。

OBJECTIVE To investigate the difference of plasma motilin (MOT) and serum gastrin (GAS) levels between breast-fed and formula-fed newborn infants. METHODS We measured MOT and GAS using a radioimmunoassay in 100 full-trem newborns, divided into two groups. (One group 50 newborns fed by breast milk, other group 50 newborns fed by formula milk.) . RESULTS The statistical result shows the MOT and GAS levels of the former group is apparently higher than that of the latter group.It demonstrates that MOT and GAS in breast milk have the same bioactivity as newborn' s endogenous MOT and GAS, and can complement the shortage of MOT and GAS in earlier development of newborn' s gastrointestinal system.CONCLUSIONS The result also proves the advantage of breast feeding in gastrointestinal hormone levels.