摘要
本文采用亚铜作催化剂，研究了β受体显像剂－碘（１３ｌ）标记间碘苄胍的方法。１００℃水浴１０～１５分钟，标记率可达９９．９％。和经典的固相催化法相比，它不但快速、方便，而且不存在碘的损失和污染。该法可望将ＭＩＢＧ制成药盒以供临床大量使用。
A new method
for fast preparation of β-receptor imaging agent:131I labelled m-io-dobenzyl guanidine (MIBG)
was studied using Cu+ as catalyst. Labelling conditions have beenoptimised. A radiochemical
yield more than 99%is obtained at l00℃ within 10 15min. Themethod is superior to earlier
described methods, and it fulfills the requirments for kit labelling.
出处
《军医进修学院学报》
CAS
1994年第2期124-126,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
胍乙啶
类似物
衍生物
放射性核素显像
碘
Guanethidine
Analogs
and derivatives
Radionuclide imaging
lodine
Beta receptors
