青年人大肠癌临床病理特点及预后分析

Investigation of clinicopathologic features and prognosis in young patients with colorectal cancer

目的探讨青年人大肠癌临床病理及预后特点。方法分析88例青年人大肠癌的临床、内镜、病理、预后情况并与同期483例中老年人比较。结果两组粘液血便、排便习惯异常、高分化腺癌、粘液腺癌、未分化癌、DukesB1期、DukesD期和根治性切除率比较,差异有显著意义(P<0.05)。结论青年人大肠癌分化较差但根治性切除率高,5年生存率与中老年人相近。

Objective To investigate the features of clinicopathology and prognosis in young patients with colorectal cancer.Methods The clinicopathologic features and survival stages of 88 young patients(age≤35,group A) with colorectal cancer were analysed compared with those of contemporaneous 483 middl-old aged patients(group B).Results The rate of muco-bloody stools,change of bowel movement habit,high differentiated adenocarcinoma,mucinous adenocarcinoma,undifferentiated carcinoma,Dukes stage B_1,Dukes D and radical resection in group A were compared with those in group B were significant difference(P<0.05).Conclusion In young patients with colorectal cancer,the differentiation of tumour is poorer but the rate of radical resection is higher,and the 5-years survival rate has no significant difference compared with middle old aged patients.