摘要
目的 研究甲状腺自身抗体在亚临床甲状腺功能亢进症(简称甲亢)中的意义.方法 以51名健康人为对照,对86例亚临床甲亢患者用微粒子酶免疫法(MEIA)测定甲状腺球蛋白抗体(TGAb)和甲状腺过氧化物酶抗体(TPOAb).结果 在亚临床甲亢患者中TGAb、TPOAb阳性率和数值明显增高,对其中73例进行12～18个月的随访发现,临床甲亢(11%)和临床甲状腺功能减退症(23%)的发生率较高.结论 测定甲状腺自身抗体对指导亚临床甲亢的治疗具有重要意义.
Objective To study the significance of thyroid autoantibodies determination in subclinical hyperthyroidism. Methods Antibody to thyroglobulin (TGAb) and antibody to thyroid-peroxidase (TPOAb) were measured in 86 cases of subclinical hyperthyroidism by microparticle enzyme immunoassay (MEIA), control group was composed of 51 healthy people. Results The levels of TGAb and TPOAb of patient group were higher than that of control group, the positive rates of TGAb and TPOb were higher too. After follow-up for 1-1.5 year, higher hyperthyroidism incidence (11%) and higher hypothyroidism incidence(23%) were found respectively in 73 cases. Conclusions It is important to measure thyroid auto-antibodies for the treatment of subclinical hyperthyroidism.
出处
《检验医学》
CAS
北大核心
2005年第3期258-259,共2页
Laboratory Medicine
