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菲并吲哚里西定类生物碱的研究进展 被引量:2

Advances in Phenanthroindolizidine Alkaloids Research
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摘要 天然来源的药物研究近年来方兴未艾,菲并吲哚里西定类生物碱目具有抗肿瘤等生理活性而倍受关注.对自然界中存在的菲并吲哚里西定类生物碱的生物活性以及全合成策略进行了综述. In recent years natural medicine study has becomes fascinating. Phenan throindolizidine alkaloids, which have antitumor activity and other bioactivities, have been studied for almost fifty years. In this paper the bioactivities and total synthesis of phenanthroindolizidine alkaloids were reviewed.
出处 《四川师范大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第3期366-370,共5页 Journal of Sichuan Normal University(Natural Science)
基金 四川省教育厅科研基金资助项目
关键词 菲并吲哚里西定生物碱 细胞毒活性 构效关系 全合成 Phenanthroindolizidine alkaloids Cytotoxic activity Structure-activity relationship Total synthesis
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同被引文献15

  • 1ZhongJIN ShiPuLI QingMinWANG RunQiuHUANG.A Concise Total Synthesis of S-(+)-Tylophorine[J].Chinese Chemical Letters,2004,15(10):1164-1166. 被引量:1
  • 2王远兴,方志杰,高军峰,王煜,丁磊,殷晓进,韩雪莲.由藜芦醛合成娃儿藤碱[J].应用化学,2007,24(2):215-219. 被引量:5
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  • 5Kinuko Iwasa,Miyoko Kamigauchi,Narao Takao,Wolfgang Wiegrebe.The Preparation of the Biosynthetic Precursor 3,7-Dihydroxy-2,6-Dimethoxyphenanthroindolizidine. Journal of Natural Products . 1988
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  • 7Wenli Gao,Scott Bussom,Susan P. Grill,Elizabeth A. Gullen,You-Cai Hu,Xueshi Huang,Sanbao Zhong,Conrad Kaczmarek,Julio Gutierrez,Samson Francis,David C. Baker,Shishan Yu,Yung-Chi Cheng.??Structure–activity studies of phenanthroindolizidine alkaloids as potential antitumor agents(J)Bioorganic & Medicinal Chemistry Letters . 2007 (15)
  • 8Zaiguo Li,Zhong Jin,Runqiu Huang.??Isolation, Total Synthesis and Biological Activity of Phenanthroindolizidine and Phenanthroquinolizidine Alkaloids(J)Synthesis . 2001 (16)
  • 9Songtao Li,Li Han,Liang Sun,Dan Zheng,Jiang Liu,Yingbo Fu,Xueshi Huang,Zhanyou Wang.Synthesis and Antitumor Activities of Phenanthrene-Based Alkaloids. Molecules . 2009
  • 10Wenli Gao,Wing Lam,Sanbao Zhong,Conrad Kaczmarek,David C. Baker,Yung-Chi Che.Novel Mode of Action of Tylophorine Analogs as Antitumor Compounds. Cancer Research . 2004

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