女性高泌乳素血症102例临床分析

Clinical Analysis of 102 Cases of Woman Hyperprolaceinemia

目的:探讨高泌乳素血症(HPL)患者的发病原因、临床特点及其诊治原则。方法:选择妇科门诊HPL患者102例,根据实验室及辅助检查,明确发病原因,针对病因用溴隐亭治疗或手术治疗。结果:HPL患者102例中垂体泌乳素瘤占60.79%,空蝶鞍综合征1.96%,甲低4.90%,药物因素6.86%,25.49%无明确病因。结论:垂体泌乳素腺瘤是女性HPL最常见的原因,常伴随性激素低下,表现为月经稀少、闭经、泌乳、不孕、习惯性流产等。治疗上主要针对病因处理,泌乳素瘤主张药物治疗,对于特发性HPL应用溴隐停与否,取决于治疗目的,且不必长期用药。

Objective :To explore the etiology, clinical characteristic ,diagnosis and treatment of hyperprolaceinemia patients.Method:We studied 102 cases of HPL patients in the gynecology clinic of our hospital.We confirmed their pathogeny with the laboratory and assistant examination and treated them with bromoeriptin or operation according to the pathogeny.Result:The pathogeny of the 102 HPL patients are prolactinoma (60.79%),empty sella syndrome(1.96%), hypothyroidism(4.90%), drug agent(6.86%) and unknown causes (25.49%).Conclusion:The very common pathogeny of woman HPL is prolactinoma that followed by low sex hormone.The symptoms of prolactinoma are spanomenorrhea, amenorrha,galactorrhea,sterility and recurrent abortion,etc.We treated them according to their pathogeny.Prolactinoma patients were treated with drugs.Whether we use bromoeriptin or not is determined by treatment chronically.