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用ELISA法检测GSH-PX活性及其在克山病病区儿童中的初步应用 被引量:1

ELISA IN DETECTION OF BLOOD GSH-PX AND ITS PRELIMINARY APPLICATION IN KESHAN DISEASE
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摘要 本文建立了检测血GSH-px 的ELISA 双抗体夹心法。用此方法对克山病病区患儿及健康儿童的血液GSH-px 活力进行了测定。发现病区慢型克山病、潜在型克山病以及健康儿童血GSH-px 活力均明显低于非病区健康儿童(p<0.01);慢型克山病患儿血GSH-px 活力低于病区健康儿童(p<0.05);病区健康儿童血GSH-px 活力与潜在型克山病患儿无差异(p>0.05)。本文对实验方法及结果进行了初步讨论。 An ELISA bi-antibody sandwich for thedetection of human blood GSH-px has beenestablished.GSH-px activities were deter-mined ELISA in children in Keshan diseaseeffected aras and non-effected areas.Theresults showed that the blood GSH-px acti- vities in the children(latent type,chronictype anti healthy children)in the Keshandisease effected areas were lower than thesein the non-effected areas,with a signifi-cant difference(P<0.01),However,theblood GSH-px activities in chronic typechildren were lower than in healthy child-ren in the Keshan disease effected areas(P<0.05).
出处 《西安医科大学学报》 CSCD 1989年第1期29-32,共4页 Journal of Xi'an Medical University(Chinese)
基金 国家自然科学基金
关键词 ELISA GSH-PX 克山病 ELISA GSH-px Keshan disease
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  • 1关金阳,黄绍明,李芳生.克山病患儿红细胞及尸体心肌的硒及谷胱甘肽过氧化物酶活性分析[J]中国地方病防治杂志,1987(04).

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