立普妥在器官移植上应用综述

Atorvastatin application of transplantation

立普妥是3-羟基-3-甲基-戊二酰辅酶A(HMG-C0A)还原酶抑制剂中的新成员,在降血脂药中疗效显著;而在器官移植的应用过程中,发现立普妥有着特殊作用。本文就立普妥在器官移植中,有关其影响降脂、血管损伤、免疫抑制、影响预后、并发症等方面的当前研究工作进行讨论。

Hydroxymethylglutary coenzyme A reductase inhibitors-new member Atorvastatin has an significant efiertive lowing blood-lipid. And while be used in transplantation, atorvastatin has exceptional functions. In this review, we focus on discussing some previous researches about lowing blood fat, injuring blood vessel, affecting immunosuppression and complication during atorvastin's application.