摘要
RNAi是双链RNA介导的、序列特异性的转录后基因沉默, 自1998 年发现至今已有很大进展.本文综述了RNA 干涉的分子机理及其应用研究进展.
RNA interference (RNAi) is the process of sequence-specific post-transcriptional gene silencing in animals and plants initiated by double-stranded RNA (dsRNA).It advanced at a miraculous pace since it was discovered in 1998. Here the mechanism and application of RNAi are reviewed.
作者
邓小莉
DENG Xiao-li (Department of applied Biology, Pingyuan University, Xinxiang,Henan 453003 China)
出处
《平原大学学报》
2005年第3期104-109,共6页
Journal of Pingyuan University
关键词
RNAI
共抑制
功能基因组
DSRNA
siRNA
基因沉默
RNA interference
co-suppression
functional genomics
double-stranded RNA (dsRNA)
small interfering RNA (siRNA)
gene silencing.
