摘要
对63只置铜宫内节育器大鼠子宫毛细血管脆性、通透性和内膜血流量进行了分区测量。结果显示,14例墨汁高压灌流标本的环压区内膜均有出血,出血率为100%,与其它各区相比差异显著;千宫组织中伊文思蓝的含量环压区和邻环区明显高于其他各区。应用比受体阻断剂后,环压区与其他各区仍有显著差异;子官内膜的血流量以对压区作为100%,对邻区、对远区、远环区和邻环区分别为109.4%、116.6%、118.9%和107.6%。环压区为83.4%,显著低于以上各区。这表明铜宫内节育器可引起与其接触的内膜毛细血管脆性、通透性增加,血流量减少,可能是带器出血的重要原因。
In the present study,the fragility and permeability of endometrial capillaries and2ndometrial blood flow volume in various areas were ineasured in 63 rats with Cu-IUD。The resultsshowed that bleeding was observed in IUD-pressed are of l4 speciniens after high pressure perfusion。The rate of bleeding was 100%.There was sinificant difference as compared with other areas. The con-tent of Evtans blue in the IUD-pressed and adiacent areas was siginificantly higher than that in the re-mote areas and in thet control horn.After administration of H1-receptor blocking drug, the content ofEvens blue in the IUD-pressed area remained siginificantly higher than that in the other areas. If endometr blood flow volume served as l00%in the area of IUD-pressed control,it was109.4%,116.6%,118.9%and l07.6%respectiveiy in the areas of adjacent control,remote control,andareas remote and,adjacent to IUD The endometrial blood flow volume in IUD-pressed area was 83.4%。which was significantly lower than those of other areas. It was suggested that increase of fragility andpermeability of endometuial capillaries and decrease of endometrial blood flow volume in IUD-pressedarea are among the important reasons of IUD induced bleeding.
出处
《生殖医学杂志》
CAS
1994年第2期94-97,共4页
Journal of Reproductive Medicine
关键词
毛细血管
脆性
通透性
血流量
宫内节育器
Intrauterine device Capillary fragility Capillary permeability Blood flow volume