肺炎克雷伯菌致婴幼儿腹泻发病动态观察

Observation of Occurance of Infant Diarrhea Caused by Klebsiella Pneumoniae

目的观察肺炎克雷伯菌所致婴幼儿腹泻的发病动态与流行趋势,探索有效治疗措施。方法取腹泻患儿新鲜大便,送作细菌培养,从中筛查出肺炎克雷伯菌所致病例,进行整理分析。结果从大便培养阳性的1005例病例中,筛查出肺炎克雷伯菌322例,占32%,居同期病原菌之首。年龄均在3岁以下,其中1岁以内婴儿占71.7%,夏秋季为发病高峰。结论肺炎克雷伯菌是人体肠道正常寄居菌之一,当机体抵抗力低下时,可致婴幼儿腹泻,成为重要的条件致病菌,其发病的流行因素与年龄、免疫力、季节、喂养方式及抗生素的应用等多种因素有关。近几年来,发病人数呈逐年上升趋势,提请临床儿科医生引起关注。

Objective To observe the occuring and endemic trend of infant diarrhea caused by Klebsiella pneumoniae and search for effective treatment method. Methods New stool of infant diarrhea paitents was sampled and sent for bac teria culture .Klebsiella pneumomae positive cases were selected for furthur analysis. Results In 1005 infant diarrhea cases, feces showed bacteria positive through bacteria culture 322 cases, accounting for 32%, were Klebsiella pneumoniae positive . Klebsiella pneunaoniae was indicated as the leading pathogen. All the Klebsiella pneamonine positive cases were under 3 years old and 71.7% of them were under 1 year old . Peak time of the occuring of this disease was summer and autumn. Conclusion As one of the human normal intestinal sited bacteria Klebsiella pneumoniae is an important opportunistic pathogen which can cause infant diarrhea when their immunity is low. The disease can be caused by many factors including infant age, immunity, season, feeding method, application of antibiotics and so on. The number of such cases has been increasing in these recent years. Attention should be paid to this disease from paediatricians.