摘要
用放射免疫法检测了正常人和肝炎患者血浆心钠素（ＡＮＰ）。结果表明ＡＮＰ几何均值在重型肝炎＞慢活肝＞急黄肝；动态观察表明ＡＮＰ均值在黄疸上升期＞黄疸下降期＞恢复期，均有显著差异。在重型肝炎的腹水组与无腹水组、存活组与死亡组，ＡＮＰ也有显著差异，实验提示ＡＮＰ代谢紊乱可能是机体水钠失调的标志之一。我们还测定了肝组织中ＡＮＰ，初步认为肝组织内ＡＮＰ随病情不同而含量亦有差异。
he plasma levels of ANP were measured in normal
individuals and patients with various viral hepatitis.The results
showed that plasma level of ANP in patients with fulminant hepatitis
was the highest,the secondhigh was that of chronic active hepatitis
and the level of ANP in patients with acute icterohepatitis was
thelowest.The level of ANP during jaundice increase period was the
highest,the second high was during jaun-dice decrease period and the
third was in convalescence. A significant difference of ANP level was
demonstratedbetween ascite group and ascite-free group and between
survival group and group died of fulminant hepatitis.Our results
suggest that the metabolic disorder of ANP seems to be one of the
marks of modulating imbalance-from water and salt.ANP in liver tissue
was also measured.The preliminary conclusion is that the
ANPcon-centrations in the liver tissue are different in patients with
different clinical conditions.
