摘要
A poly(N-isopropylacrylamide)/β-Cyclodextr in (PNIPAM/β-CD) ionic polymer was synthesized by the reaction of poly( N-isopropylacrylamide-co-acryl acid) (poly(NIPAM-co-AA) with mo no-6-ethanolamine-β-cyclodextrin (EAA-β-CD).EAA-β-CD was synthesized via the reaction of mono-6-OTs-β-CD(Ts= p-toluensulfo nyl) with E.The ionic polymer was characterized by means of FT-IR and UV-V isi ble spectroscopes,and DSC.The result shows that the formation of ionic interacti on between poly(NIPAM-co-) and E-β-CD leads to an increase of t he glass transition temperature (T g) of poly(NIPAM-co-).In additio n,not only the ionic polymer exhibits a well-defined lower critical solution te mperature (LCST),but also β-CD on the polymer backbone can be modulated by changing the pH values,as compared with β-CD-conjugated polymers with co valent bonds.Also,β-CD can easily be bound to the polymer backbone in form of free,or inclusion complex.It is expected that the polymer may find some usef ul applications such as drug delivery system.
A poly(N-isopropylacrylamide)/β-Cyclodextr in (PNIPAM/β-CD) ionic polymer was synthesized by the reaction of poly( N-isopropylacrylamide-co-acryl acid) (poly(NIPAM-co-AA) with mo no-6-ethanolamine-β-cyclodextrin (EAA-β-CD).EAA-β-CD was synthesized via the reaction of mono-6-OTs-β-CD(Ts= p-toluensulfo nyl) with E.The ionic polymer was characterized by means of FT-IR and UV-V isi ble spectroscopes,and DSC.The result shows that the formation of ionic interacti on between poly(NIPAM-co-) and E-β-CD leads to an increase of t he glass transition temperature (T g) of poly(NIPAM-co-).In additio n,not only the ionic polymer exhibits a well-defined lower critical solution te mperature (LCST),but also β-CD on the polymer backbone can be modulated by changing the pH values,as compared with β-CD-conjugated polymers with co valent bonds.Also,β-CD can easily be bound to the polymer backbone in form of free,or inclusion complex.It is expected that the polymer may find some usef ul applications such as drug delivery system.
出处
《高分子学报》
SCIE
CAS
CSCD
北大核心
2005年第3期471-475,共5页
Acta Polymerica Sinica
基金
国家自然科学基金 (基金号 2 0 3 740 40 )资助项目
