Cypher与Taxus支架治疗冠心病的冠状动脉造影随访结果

Angiographic follow-up study of the effect of the Cypher and Taxus stents in coronary antery disease

目的观察Cypher及Taxus药物洗脱支架治疗冠心病的疗效。方法应用冠状动脉造影随访162例接受Cypher及Taxus药物洗脱支架置入术的冠心病患者,其中Cypher组93例,Taxus组69例。结果Cypher组和Taxus组再狭窄率分别为10.8%和11.6%,靶病变再血管化率分别为5.4%和5.8%,两组比较差异均无统计学意义。支架内晚期管径丢失及支架节段晚期管径丢失在Cypher组低于Taxus组,两组间差异有统计学意义。结论药物洗脱支架可有效降低介入治疗术后再狭窄的发生率,但Cypher组支架内晚期管径丢失低于Taxus组。

Objective To evaluate the efficacy of Cypher and Taxus drug eluting stent (DES)in the treatment of coronary artery diease. Methods A total 162 patients underwent coronary artery stenting with eigher the Cypher (n=93) or the Taxus (n=69) drug eluting stent. All patients received follow up angiography. Results The angiographic restenosis rate and TLR rate were 10.8% and 5.4% in the Cypher group whereas 11.6% and 5.8% in the Taxus group. There were no statistical differences between the two groups. In-Stent Late Loss and In-Lesion Late Loss were found less in the Cypher group than in the Taxus group. Conclusion Both the Cypher DES and the Taxus DES decreased the restenosis and TLR rates but the Cypher stent has a lower late loss rate than the Taxus stent.