HIV感染者微小病毒B19抗体的调查

Investigation of the Prevalence of Parvovirus B19 Antibody in People Infected with HIV

目的研究HIV感染人群微小病毒B19抗体的流行情况。方法采用ELISA方法检测126例HIV感染者和95例健康人血清中微小病毒B19-IgG、IgM抗体的阳性率,分析影响阳性率的因素。结果HIV感染人群的B19-IgG、IgM阳性率分别为61.1%和7.1%,健康人群的B19-IgG、IgM阳性率分别为17.9%和1.1%。两者均有明显的差异(P<0.05)。结论HIV感染人群微小病毒B19远期和近期感染率明显高于健康人群。

Objective To determine the prevalence of human parvovirus B19 antibody in HIV-infected people in comparison with non-HIV-infected people. Serum sampleswere collected from 126 HIV-infected and 95 non-HIV-infected people and tested for B19 IgG and IgM antibody by enzyme-linked immunoabsorbent assay (ELISA).~Methods The prevalence of anti-B19 IgG in HIV-infected and non-infected people were 61.1% and 17.9% respectively (P<0.01).~Results The prevalence of parvovirus B19 IgM was 7.1% and 1.1% in HIV-infected and non-infected people respectively (P<0.05).Conclusion There was no difference found in men and women. Blood transfusion was found to be a risk factor for presence of parvovirus antibody.